Cargando…
A Novel Benzocoumarin-Stilbene Hybrid as a DNA ligase I inhibitor with in vitro and in vivo anti-tumor activity in breast cancer models
Existing cancer therapies are often associated with drug resistance and toxicity, which results in poor prognosis and recurrence of cancer. This necessitates the identification and development of novel therapeutics against existing as well as novel cellular targets. In this study, a novel class of B...
Autores principales: | Hussain, Mohd. Kamil, Singh, Deependra Kumar, Singh, Akhilesh, Asad, Mohd., Ansari, Mohd. Imran, Shameem, Mohammad, Krishna, Shagun, Valicherla, Guru R., Makadia, Vishal, Meena, Sanjeev, Deshmukh, Amit Laxmikant, Gayen, Jiaur R., Imran Siddiqi, Mohammad, Datta, Dipak, Hajela, Kanchan, Banerjee, Dibyendu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587642/ https://www.ncbi.nlm.nih.gov/pubmed/28878282 http://dx.doi.org/10.1038/s41598-017-10864-3 |
Ejemplares similares
-
Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity
por: Valicherla, Guru R., et al.
Publicado: (2016) -
Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus
por: Hossain, Zakir, et al.
Publicado: (2018) -
Simultaneous Estimation of Quercetin and trans-Resveratrol in Cissus quadrangularis Extract in Rat Serum Using Validated LC-MS/MS Method: Application to Pharmacokinetic and Stability Studies
por: Dadge, Shailesh D., et al.
Publicado: (2023) -
Crystal structure of 7,8-benzocoumarin-4-acetic acid
por: Swamy, R. Ranga, et al.
Publicado: (2015) -
Evaluation of the Pharmacokinetics of the Pancreastatin Inhibitor PSTi8 Peptide in Rats: Integration of In Vitro and In Vivo Findings
por: Valicherla, Guru R., et al.
Publicado: (2022)