Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model

Septic acute kidney injury (AKI) associates with poor survival rates and often requires renal replacement therapy. Glucocorticoids may pose renal protective effects in sepsis via stimulation of mitochondrial function. Therefore, we studied the mitochondrial effects of dexamethasone in an experimenta...

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Detalles Bibliográficos
Autores principales: Schirris, T. J. J., Jansen, J., Mihajlovic, M., van den Heuvel, L. P., Masereeuw, R., Russel, F. G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587643/
https://www.ncbi.nlm.nih.gov/pubmed/28878224
http://dx.doi.org/10.1038/s41598-017-10483-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587643/
https://www.ncbi.nlm.nih.gov/pubmed/28878224
http://dx.doi.org/10.1038/s41598-017-10483-y

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