An in-silico approach to predict and exploit synthetic lethality in cancer metabolism

Synthetic lethality is a promising concept in cancer research, potentially opening new possibilities for the development of more effective and selective treatments. Here, we present a computational method to predict and exploit synthetic lethality in cancer metabolism. Our approach relies on the con...

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Detalles Bibliográficos
Autores principales: Apaolaza, Iñigo, San José-Eneriz, Edurne, Tobalina, Luis, Miranda, Estíbaliz, Garate, Leire, Agirre, Xabier, Prósper, Felipe, Planes, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587678/
https://www.ncbi.nlm.nih.gov/pubmed/28878380
http://dx.doi.org/10.1038/s41467-017-00555-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587678/
https://www.ncbi.nlm.nih.gov/pubmed/28878380
http://dx.doi.org/10.1038/s41467-017-00555-y

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