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Gas6 derived from cancer-associated fibroblasts promotes migration of Axl-expressing lung cancer cells during chemotherapy

Alterations to the tumor stromal microenvironment induced by chemotherapy could influence the behavior of cancer cells. In the tumor stromal microenvironment, cancer-associated fibroblasts (CAFs) play an important role. Because the receptor tyrosine kinase Axl and its ligand Gas6 could be involved i...

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Detalles Bibliográficos
Autores principales: Kanzaki, Ryu, Naito, Hisamichi, Kise, Kazuyoshi, Takara, Kazuhiro, Eino, Daisuke, Minami, Masato, Shintani, Yasushi, Funaki, Soichiro, Kawamura, Tomohiro, Kimura, Toru, Okumura, Meinoshin, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587707/
https://www.ncbi.nlm.nih.gov/pubmed/28878389
http://dx.doi.org/10.1038/s41598-017-10873-2