Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2

Reactive oxygen species are produced transiently in response to cell stimuli, and function as second messengers that oxidize target proteins. Protein-tyrosine phosphatases are important reactive oxygen species targets, whose oxidation results in rapid, reversible, catalytic inactivation. Despite inc...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Ryouhei, Harizanova, Jana, Stockert, Rabea, Schröder, Katrin, Bastiaens, Philippe I. H., Neel, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587708/
https://www.ncbi.nlm.nih.gov/pubmed/28878211
http://dx.doi.org/10.1038/s41467-017-00503-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587708/
https://www.ncbi.nlm.nih.gov/pubmed/28878211
http://dx.doi.org/10.1038/s41467-017-00503-w

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