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Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2
Reactive oxygen species are produced transiently in response to cell stimuli, and function as second messengers that oxidize target proteins. Protein-tyrosine phosphatases are important reactive oxygen species targets, whose oxidation results in rapid, reversible, catalytic inactivation. Despite inc...
Autores principales: | Tsutsumi, Ryouhei, Harizanova, Jana, Stockert, Rabea, Schröder, Katrin, Bastiaens, Philippe I. H., Neel, Benjamin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587708/ https://www.ncbi.nlm.nih.gov/pubmed/28878211 http://dx.doi.org/10.1038/s41467-017-00503-w |
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