Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer

Dynamins are mechano-chemical GTPases involved in the remodeling of cellular membranes. In this study, we have investigated the mechanism of dynamin-related protein 1 (Drp1), a key mediator of mitochondrial fission. To date, it is unclear how Drp1 assembles on the mitochondrial outer membrane in res...

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Detalles Bibliográficos
Autores principales: Francy, Christopher A., Clinton, Ryan W., Fröhlich, Chris, Murphy, Colleen, Mears, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587723/
https://www.ncbi.nlm.nih.gov/pubmed/28878368
http://dx.doi.org/10.1038/s41598-017-11008-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587723/
https://www.ncbi.nlm.nih.gov/pubmed/28878368
http://dx.doi.org/10.1038/s41598-017-11008-3

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