Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu

While most DNA polymerases discriminate against ribonucleotide triphosphate (rNTP) incorporation very effectively, the Family X member DNA polymerase μ (Pol μ) incorporates rNTPs almost as efficiently as deoxyribonucleotides. To gain insight into how this occurs, here we have used X-ray crystallogra...

Descripción completa

Detalles Bibliográficos
Autores principales: Moon, Andrea F., Pryor, John M., Ramsden, Dale A., Kunkel, Thomas A., Bebenek, Katarzyna, Pedersen, Lars C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587726/
https://www.ncbi.nlm.nih.gov/pubmed/28911097
http://dx.doi.org/10.1093/nar/gkx527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587726/
https://www.ncbi.nlm.nih.gov/pubmed/28911097
http://dx.doi.org/10.1093/nar/gkx527

Ejemplares similares