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Molecular mechanisms governing microRNA-125a expression in human hepatocellular carcinoma cells

MicroRNA-125a-5p (miR-125a) is a vertebrate homolog of lin-4, the first discovered microRNA, and plays a fundamental role in embryo development by downregulating Lin-28 protein. MiR-125a is also expressed in differentiated cells where it generally acts as an antiproliferative factor by targeting mem...

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Detalles Bibliográficos
Autores principales: Potenza, Nicoletta, Panella, Marta, Castiello, Filomena, Mosca, Nicola, Amendola, Elena, Russo, Aniello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587745/
https://www.ncbi.nlm.nih.gov/pubmed/28878257
http://dx.doi.org/10.1038/s41598-017-11418-3