A natural chalcone induces apoptosis in lung cancer cells: 3D-QSAR, docking and an in vivo/vitro assay

This study was to study the antitumor effect of lonchocarpin (34) from traditional herbal medicine Pongamia pinnata (L.) Pierre and to reveal the underlying mechanism. The cytotoxic activities of lonchocarpin were evaluated in 10 lung cancer cell lines and it exhibited 97.5% activity at a dose of 10...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Zhou, Di, Li, Xue-Zheng, Jiang, Zhe, Tan, Chengyu, Wei, Xiu-Yan, Ling, Junhong, Jing, Jing, Liu, Fen, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587747/
https://www.ncbi.nlm.nih.gov/pubmed/28878321
http://dx.doi.org/10.1038/s41598-017-11369-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587747/
https://www.ncbi.nlm.nih.gov/pubmed/28878321
http://dx.doi.org/10.1038/s41598-017-11369-9

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