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A natural chalcone induces apoptosis in lung cancer cells: 3D-QSAR, docking and an in vivo/vitro assay
This study was to study the antitumor effect of lonchocarpin (34) from traditional herbal medicine Pongamia pinnata (L.) Pierre and to reveal the underlying mechanism. The cytotoxic activities of lonchocarpin were evaluated in 10 lung cancer cell lines and it exhibited 97.5% activity at a dose of 10...
Autores principales: | Chen, Gang, Zhou, Di, Li, Xue-Zheng, Jiang, Zhe, Tan, Chengyu, Wei, Xiu-Yan, Ling, Junhong, Jing, Jing, Liu, Fen, Li, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587747/ https://www.ncbi.nlm.nih.gov/pubmed/28878321 http://dx.doi.org/10.1038/s41598-017-11369-9 |
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