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Flipping states: a few key residues decide the winning conformation of the only universally conserved transcription factor

Transcription factors from the NusG family bind to the elongating RNA polymerase to enable synthesis of long RNAs in all domains of life. In bacteria, NusG frequently co-exists with specialized paralogs that regulate expression of a small set of targets, many of which encode virulence factors. Esche...

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Detalles Bibliográficos
Autores principales: Shi, Da, Svetlov, Dmitri, Abagyan, Ruben, Artsimovitch, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587751/
https://www.ncbi.nlm.nih.gov/pubmed/28605514
http://dx.doi.org/10.1093/nar/gkx523