FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids

The FANCJ DNA helicase is linked to hereditary breast and ovarian cancers as well as bone marrow failure disorder Fanconi anemia (FA). Although FANCJ has been implicated in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR), the molecular mechanism underlying the tumor su...

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Detalles Bibliográficos
Autores principales: Nath, Sarmi, Somyajit, Kumar, Mishra, Anup, Scully, Ralph, Nagaraju, Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587752/
https://www.ncbi.nlm.nih.gov/pubmed/28911102
http://dx.doi.org/10.1093/nar/gkx586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587752/
https://www.ncbi.nlm.nih.gov/pubmed/28911102
http://dx.doi.org/10.1093/nar/gkx586

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