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Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells

Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions. However, there are limited data regarding the pursuant feedback between p53 transactivation and thiamine homeos...

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Detalles Bibliográficos
Autores principales: Chornyy, Sergiy, Parkhomenko, Yulia, Chorna, Nataliya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587765/
https://www.ncbi.nlm.nih.gov/pubmed/28878400
http://dx.doi.org/10.1038/s41598-017-10878-x