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Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells
Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions. However, there are limited data regarding the pursuant feedback between p53 transactivation and thiamine homeos...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587765/ https://www.ncbi.nlm.nih.gov/pubmed/28878400 http://dx.doi.org/10.1038/s41598-017-10878-x |