Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting

Imprinted genes are regulated by allele-specific differentially DNA-methylated regions (DMRs). Epigenetic methylation of the CpGs constituting these DMRs is established in the germline, resulting in a 5-methylcytosine-specific pattern that is tightly maintained in somatic tissues. Here, we show a no...

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Detalles Bibliográficos
Autores principales: Patiño-Parrado, Iris, Gómez-Jiménez, Álvaro, López-Sánchez, Noelia, Frade, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587773/
https://www.ncbi.nlm.nih.gov/pubmed/28605464
http://dx.doi.org/10.1093/nar/gkx518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587773/
https://www.ncbi.nlm.nih.gov/pubmed/28605464
http://dx.doi.org/10.1093/nar/gkx518

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