Cargando…
Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting
Imprinted genes are regulated by allele-specific differentially DNA-methylated regions (DMRs). Epigenetic methylation of the CpGs constituting these DMRs is established in the germline, resulting in a 5-methylcytosine-specific pattern that is tightly maintained in somatic tissues. Here, we show a no...
Autores principales: | Patiño-Parrado, Iris, Gómez-Jiménez, Álvaro, López-Sánchez, Noelia, Frade, José M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587773/ https://www.ncbi.nlm.nih.gov/pubmed/28605464 http://dx.doi.org/10.1093/nar/gkx518 |
Ejemplares similares
-
DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding
por: Thomas, Stacey L, et al.
Publicado: (2023) -
The impact of intragenic CpG content on gene expression
por: Bauer, Asli Petra, et al.
Publicado: (2010) -
Cytosine methylation at CpCpG sites triggers accumulation of non-CpG methylation in gene bodies
por: Zabet, Nicolae Radu, et al.
Publicado: (2017) -
Human mitochondrial DNA is extensively methylated in a non-CpG context
por: Patil, Vibha, et al.
Publicado: (2019) -
No evidence of extensive non-CpG methylation in mtDNA
por: Guitton, Romain, et al.
Publicado: (2022)