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MicroRNA-449a deficiency promotes colon carcinogenesis

MicroRNAs have broad roles in tumorigenesis and cell differentiation through regulation of target genes. Notch signaling also controls cell differentiation and tumorigenesis. However, the mechanisms through which Notch mediates microRNA expression are still unclear. In this study, we aimed to identi...

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Detalles Bibliográficos
Autores principales: Niki, Masanori, Nakajima, Kohei, Ishikawa, Daichi, Nishida, Jun, Ishifune, Chieko, Tsukumo, Shin-ichi, Shimada, Mitsuo, Nagahiro, Shinji, Mitamura, Yoshinori, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587792/
https://www.ncbi.nlm.nih.gov/pubmed/28878284
http://dx.doi.org/10.1038/s41598-017-10500-0