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Coupling transcriptional activation of CRISPR–Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus

CRISPR–Cas system provides the adaptive immunity against invading genetic elements in prokaryotes. Recently, we demonstrated that Csa3a regulator mediates spacer acquisition in Sulfolobus islandicus by activating the expression of Type I-A adaptation cas genes. However, links between the activation...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Liu, Zhenzhen, Ye, Qing, Pan, Saifu, Wang, Xiaodi, Li, Yingjun, Peng, Wenfang, Liang, Yunxiang, She, Qunxin, Peng, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587795/
https://www.ncbi.nlm.nih.gov/pubmed/28911114
http://dx.doi.org/10.1093/nar/gkx612