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A systematic comparison of error correction enzymes by next-generation sequencing

Gene synthesis, the process of assembling gene-length fragments from shorter groups of oligonucleotides (oligos), is becoming an increasingly important tool in molecular and synthetic biology. The length, quality and cost of gene synthesis are limited by errors produced during oligo synthesis and su...

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Detalles Bibliográficos
Autores principales: Lubock, Nathan B., Zhang, Di, Sidore, Angus M., Church, George M., Kosuri, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587813/
https://www.ncbi.nlm.nih.gov/pubmed/28911123
http://dx.doi.org/10.1093/nar/gkx691