Overexpression of Exportin-5 Overrides the Inhibitory Effect of miRNAs Regulation Control and Stabilize Proteins via Posttranslation Modifications in Prostate Cancer()()

Although XPO5 has been characterized to have tumor-suppressor features in the miRNA biogenesis pathway, the impact of altered expression of XPO5 in cancers is unexplored. Here we report a novel “oncogenic” role of XPO5 in advanced prostate cancer. Using prostate cancer models, we found that excess l...

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Detalles Bibliográficos
Autores principales: Höti, Naseruddin, Yang, Shuang, Aiyetan, Paul, Kumar, Binod, Hu, Yingwei, Clark, David, Eroglu, Arife Unal, Shah, Punit, Johnson, Tamara, Chowdery, Wasim H., Zhang, Hui, Rodriguez, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587889/
https://www.ncbi.nlm.nih.gov/pubmed/28881308
http://dx.doi.org/10.1016/j.neo.2017.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587889/
https://www.ncbi.nlm.nih.gov/pubmed/28881308
http://dx.doi.org/10.1016/j.neo.2017.07.008

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