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An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans

Across metazoans, innate immunity is vital in defending organisms against viral infection. In mammals, antiviral innate immunity is orchestrated by interferon signaling, activating the STAT transcription factors downstream of the JAK kinases to induce expression of antiviral effector genes. In the n...

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Detalles Bibliográficos
Autores principales: Tanguy, Mélanie, Véron, Louise, Stempor, Przemyslaw, Ahringer, Julie, Sarkies, Peter, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587905/
https://www.ncbi.nlm.nih.gov/pubmed/28874466
http://dx.doi.org/10.1128/mBio.00924-17