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Dehydrosqualene Desaturase as a Novel Target for Anti-Virulence Therapy against Staphylococcus aureus

Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), is a life-threatening pathogen in hospital- and community-acquired infections. The golden-colored carotenoid pigment of S. aureus, staphyloxanthin, contributes to the resistance to reactive oxygen species (ROS) and host neutro...

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Detalles Bibliográficos
Autores principales: Gao, Peng, Davies, Julian, Kao, Richard Yi Tsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587911/
https://www.ncbi.nlm.nih.gov/pubmed/28874472
http://dx.doi.org/10.1128/mBio.01224-17