Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm

The trimethoprim and sulfamethoxazole combination, co-trimoxazole, plays a vital role in the treatment of Burkholderia pseudomallei infections. Previous studies demonstrated that the B. pseudomallei BpeEF-OprC efflux pump confers widespread trimethoprim resistance in clinical and environmental isola...

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Detalles Bibliográficos
Autores principales: Podnecky, Nicole L., Rhodes, Katherine A., Mima, Takehiko, Drew, Heather R., Chirakul, Sunisa, Wuthiekanun, Vanaporn, Schupp, James M., Sarovich, Derek S., Currie, Bart J., Keim, Paul, Schweizer, Herbert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587915/
https://www.ncbi.nlm.nih.gov/pubmed/28874476
http://dx.doi.org/10.1128/mBio.01357-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587915/
https://www.ncbi.nlm.nih.gov/pubmed/28874476
http://dx.doi.org/10.1128/mBio.01357-17

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