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PCDH8 inhibits glioma cell proliferation by negatively regulating the AKT/GSK3β/β-catenin signaling pathway

Protocadherin-8 (PCDH8), a member of the protocadherin superfamily of proteins, is frequently lost in numerous types of cancer. However, the role that PCDH8 serves in human glioma, and the molecular mechanisms underlying this, remain unclear. Data from the present study demonstrated that the express...

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Detalles Bibliográficos
Autores principales: Zong, Zhenkun, Pang, Hui, Yu, Rutong, Jiao, Yunqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588001/
https://www.ncbi.nlm.nih.gov/pubmed/28927088
http://dx.doi.org/10.3892/ol.2017.6629