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Cell Adhesion on RGD-Displaying Knottins with Varying Numbers of Tryptophan Amino Acids to Tune the Affinity for Assembly on Cucurbit[8]uril Surfaces

[Image: see text] Cell adhesion is studied on multivalent knottins, displaying RGD ligands with a high affinity for integrin receptors, that are assembled on CB[8]-methylviologen-modified surfaces. The multivalency in the knottins stems from the number of tryptophan amino acid moieties, between 0 an...

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Detalles Bibliográficos
Autores principales: Sankaran, Shrikrishnan, Cavatorta, Emanuela, Huskens, Jurriaan, Jonkheijm, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588093/
https://www.ncbi.nlm.nih.gov/pubmed/28514856
http://dx.doi.org/10.1021/acs.langmuir.7b00702