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Oxygen-Dependent Lipid Profiles of Three-Dimensional Cultured Human Chondrocytes Revealed by MALDI-MSI

[Image: see text] Articular cartilage is exposed to a gradient of oxygen levels ranging from 5% at the surface to 1% in the deepest layers. While most cartilage research is performed in supraphysiological oxygen levels (19–21%), culturing chondrocytes under hypoxic oxygen levels (≤8%) promotes the c...

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Detalles Bibliográficos
Autores principales: Bakker, Brenda, Eijkel, Gert B., Heeren, Ron M. A., Karperien, Marcel, Post, Janine N., Cillero-Pastor, Berta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588094/
https://www.ncbi.nlm.nih.gov/pubmed/28727417
http://dx.doi.org/10.1021/acs.analchem.7b02265