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Oxygen-Dependent Lipid Profiles of Three-Dimensional Cultured Human Chondrocytes Revealed by MALDI-MSI
[Image: see text] Articular cartilage is exposed to a gradient of oxygen levels ranging from 5% at the surface to 1% in the deepest layers. While most cartilage research is performed in supraphysiological oxygen levels (19–21%), culturing chondrocytes under hypoxic oxygen levels (≤8%) promotes the c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588094/ https://www.ncbi.nlm.nih.gov/pubmed/28727417 http://dx.doi.org/10.1021/acs.analchem.7b02265 |