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Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation
Rearrangement and amplification of the D-type cyclin genes have been reported in human cancer. Previous studies have demonstrated that Ras-mediated skin tumorigenesis depends on pathways that act through cyclin D1 and D2; however, the role of cyclin D3 remains unknown. The present study demonstrates...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588102/ https://www.ncbi.nlm.nih.gov/pubmed/28927034 http://dx.doi.org/10.3892/ol.2017.6551 |