Dichloroacetate induces protective autophagy in esophageal squamous carcinoma cells

Dichloroacetate (DCA) is an inhibitor of pyruvate dehydrogenase kinase, which promotes the flux of carbohydrates into mitochondria and enhances the aerobic oxidation of glucose. DCA has previously been demonstrated to exhibit antitumor properties. The present study revealed that treatment with DCA i...

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Detalles Bibliográficos
Autores principales: Jia, Hong-Yu, Wang, He-Nan, Xia, Feng-Yu, Sun, Yan, Liu, Hong-Li, Yan, Li-Li, Li, Shan-Shan, Jiang, Dong-Chun, Xu, Mei-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588168/
https://www.ncbi.nlm.nih.gov/pubmed/28928817
http://dx.doi.org/10.3892/ol.2017.6562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588168/
https://www.ncbi.nlm.nih.gov/pubmed/28928817
http://dx.doi.org/10.3892/ol.2017.6562

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