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Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cells

Cancer stem cells (CSCs) are associated with tumor initiation, therapeutic resistance, relapse and metastasis. However, the underlying mechanisms CSCs use to preserve stemness are not yet fully understood. The present study demonstrated that the expression of RAB27A, member RAS oncogene family (Rab2...

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Detalles Bibliográficos
Autores principales: Feng, Feixue, Zhang, Jianping, Fan, Xiaoxuan, Yuan, Fang, Jiang, Yinghao, Lv, Ruihua, Ma, Yanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588170/
https://www.ncbi.nlm.nih.gov/pubmed/28928832
http://dx.doi.org/10.3892/ol.2017.6542