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The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria

BACKGROUND: The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists. One approach to the development of a malaria vaccine is to target the asexual blood stage that results in clinical symptoms. Most attempts have failed. New antigens such as P...

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Detalles Bibliográficos
Autores principales: Karch, Christopher P., Doll, Tais A. P. F., Paulillo, Sara M., Nebie, Issa, Lanar, David E., Corradin, Giampietro, Burkhard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588597/
https://www.ncbi.nlm.nih.gov/pubmed/28877692
http://dx.doi.org/10.1186/s12951-017-0295-0