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Development of TaqMan probes targeting the four major celiac disease epitopes found in α-gliadin sequences of spelt (Triticum aestivum ssp. spelta) and bread wheat (Triticum aestivum ssp. aestivum)

BACKGROUND: Celiac disease (CD) is caused by specific sequences of gluten proteins found in cereals such as bread wheat (Triticum aestivum ssp. aestivum) and spelt (T. aestivum ssp. spelta). Among them, the α-gliadins display the highest immunogenicity, with four T-cell stimulatory epitopes. The tox...

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Detalles Bibliográficos
Autores principales: Dubois, Benjamin, Bertin, Pierre, Muhovski, Yordan, Escarnot, Emmanuelle, Mingeot, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588674/
https://www.ncbi.nlm.nih.gov/pubmed/28912827
http://dx.doi.org/10.1186/s13007-017-0222-2