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Positive regulation of prostate cancer cell growth by lipid droplet forming and processing enzymes DGAT1 and ABHD5

BACKGROUND: Neoplastic cells proliferate rapidly and obtain requisite building blocks by reprogramming metabolic pathways that favor growth. Previously, we observed that prostate cancer cells uptake and store lipids in the form of lipid droplets, providing building blocks for membrane synthesis, to...

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Detalles Bibliográficos
Autores principales: Mitra, Ranjana, Le, Thuc T., Gorjala, Priyatham, Goodman Jr., Oscar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588693/
https://www.ncbi.nlm.nih.gov/pubmed/28877685
http://dx.doi.org/10.1186/s12885-017-3589-6