Cargando…

Membrane‐bound Dickkopf‐1 in Foxp3(+) regulatory T cells suppresses T‐cell‐mediated autoimmune colitis

Induction of tolerance is a key mechanism to maintain or to restore immunological homeostasis. Here we show that Foxp3(+) regulatory T (Treg) cells use Dickkopf‐1 (DKK‐1) to regulate T‐cell‐mediated tolerance in the T‐cell‐mediated autoimmune colitis model. Treg cells from DKK‐1 hypomorphic doubleri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chae, Wook‐Jin, Park, Jong‐Hyun, Henegariu, Octavian, Yilmaz, Saliha, Hao, Liming, Bothwell, Alfred L. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588763/ https://www.ncbi.nlm.nih.gov/pubmed/28556921 http://dx.doi.org/10.1111/imm.12766

Ejemplares similares

T-bet Expression by Foxp3(+) T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis
por: McPherson, Rhoanne C., et al.
Publicado: (2015)

Therapeutic Potential of Gene-Modified Regulatory T Cells: From Bench to Bedside
por: Chae, Wook-Jin, et al.
Publicado: (2018)

Targeting Sirtuin-1 Alleviates Experimental Autoimmune Colitis by Induction of Foxp3+ T-Regulatory Cells: Sirt1 targeting alleviates autoimmune colitis
por: Akimova, Tatiana, et al.
Publicado: (2014)

Inflammation-induced repression of Foxp3-bound chromatin in regulatory T cells
por: Arvey, Aaron, et al.
Publicado: (2014)

Foxp3+ regulatory T cell therapy for tolerance in autoimmunity and solid organ transplantation
por: Sanders, Jes M., et al.
Publicado: (2022)

Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function
por: Ren, Jiazi, et al.
Publicado: (2019)

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity
por: Zong, Xinying, et al.
Publicado: (2021)

FOXP3(+) regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues
por: Martinez, Hunter A., et al.
Publicado: (2023)

Activated β-Catenin in Foxp3(+) Regulatory T cells Links Inflammatory Environments to Autoimmunity
por: Sumida, Tomokazu, et al.
Publicado: (2018)

Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A
por: Chae, Wook-Jin, et al.
Publicado: (2015)

Sustained suppression by Foxp3(+) regulatory T cells is vital for infectious transplantation tolerance
por: Kendal, Adrian R., et al.
Publicado: (2011)

The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4(+)Foxp3(+) Regulatory T-Cells
por: Ju, Shyr-Te, et al.
Publicado: (2012)

Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1
por: Shin, Jae Hun, et al.
Publicado: (2021)

ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells
por: Chen, Qianmei, et al.
Publicado: (2018)

Human FOXP3(+) T regulatory cell heterogeneity
por: Mohr, Audrey, et al.
Publicado: (2018)

A vitamin D receptor agonist converts CD4+ T cells to Foxp3+ regulatory T cells in patients with ulcerative colitis
por: Lu, Dong, et al.
Publicado: (2017)

Intestinal Tr1 Cells Confer Protection against Colitis in the Absence of Foxp3(+) Regulatory T Cell–Derived IL-10
por: Zhou, Julie Y., et al.
Publicado: (2023)

Deficiency of Foxp3(+) Regulatory T Cells Exacerbates Autoimmune Arthritis by Altering the Synovial Proportions of CD4(+) T Cells and Dendritic Cells
por: Jang, Eunkyeong, et al.
Publicado: (2011)

Signaling Through gp130 Compromises Suppressive Function in Human FOXP3(+) Regulatory T Cells
por: Bin Dhuban, Khalid, et al.
Publicado: (2019)

Daurinol Attenuates Autoimmune Arthritis via Stabilization of Nrp1–PTEN–Foxp3 Signaling in Regulatory T Cells
por: Park, Min-Jung, et al.
Publicado: (2019)

Protein Arginine Methyltransferase 5 Inhibition Upregulates Foxp3(+) Regulatory T Cells Frequency and Function during the Ulcerative Colitis
por: Zheng, Yingxia, et al.
Publicado: (2017)

Transient Depletion of Foxp3(+) Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice
por: Watts, Deepika, et al.
Publicado: (2021)

Abundant CD4+FOXP3+ regulatory T cells fail to suppress the proliferation of T cells in patients with Turner syndrome
por: Ah Lee, Young, et al.
Publicado: (2015)

FOXP3(+) Treg Cells and Gender Bias in Autoimmune Diseases
por: Nie, Jia, et al.
Publicado: (2015)

Effects of Natalizumab Treatment on Foxp3+ T Regulatory Cells
por: Stenner, Max-Philipp, et al.
Publicado: (2008)

Epigenetic Control of the foxp3 Locus in Regulatory T Cells
por: Floess, Stefan, et al.
Publicado: (2007)

Development of Foxp3+ regulatory T cell: epigenetics and more…
por: Hühn, Jochen
Publicado: (2011)

Functional Reprogramming of Regulatory T cells in the absence of Foxp3
por: Charbonnier, Louis-Marie, et al.
Publicado: (2019)

The Many Functions of Foxp3(+) Regulatory T Cells in the Intestine
por: Cosovanu, Catalina, et al.
Publicado: (2020)

Foxp3(+) Regulatory T Cells in Bone and Hematopoietic Homeostasis
por: Fischer, Luise, et al.
Publicado: (2019)

Ribavirin Does Not Impair the Suppressive Activity of Foxp3(+)CD4(+)CD25(+) Regulatory T Cells
por: Lee, Jeewon, et al.
Publicado: (2013)

Amelioration of autoimmune arthritis by adoptive transfer of Foxp3-expressing regulatory B cells is associated with the Treg/Th17 cell balance
por: Park, Mi Kyung, et al.
Publicado: (2016)

UXT is a novel regulatory factor of regulatory T cells associated with Foxp3
por: Li, Weina, et al.
Publicado: (2014)

Identification of a Regulatory T Cell Specific Cell Surface Molecule that Mediates Suppressive Signals and Induces Foxp3 Expression
por: Wang, Rui, et al.
Publicado: (2008)

Foxp3+ Regulatory T-cells and IL-2: The Moirai of T-cell Fates?
por: Gasteiger, Georg, et al.
Publicado: (2012)

Modification of the FoxP3 Transcription Factor Principally Affects Inducible T Regulatory Cells in a Model of Experimental Autoimmune Encephalomyelitis
por: Verhagen, Johan, et al.
Publicado: (2013)

CD3+CD4+LAP+Foxp3-Regulatory Cells of the Colonic Lamina Propria Limit Disease Extension in Ulcerative Colitis
por: Butera, Alessia, et al.
Publicado: (2018)

TAp63, a methotrexate target in CD4(+) T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis
por: Suga, Kensuke, et al.
Publicado: (2023)

Foxp3(+) regulatory T cells maintain immune homeostasis in the skin
por: Dudda, Jan C., et al.
Publicado: (2008)

Correction: Effects of Natalizumab Treatment on Foxp3+ T Regulatory Cells
por: Stenner, Max-Philipp, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ko34ok4ns64hp6ac5dgafk15ca