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pH-dependent binding of guests in the cavity of a polyhedral coordination cage: reversible uptake and release of drug molecules
A range of organic molecules with acidic or basic groups exhibit strong pH-dependent binding inside the cavity of a polyhedral coordination cage. Guest binding in aqueous solution is dominated by a hydrophobic contribution which is compensated by stronger solvation when the guests become cationic (b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588781/ https://www.ncbi.nlm.nih.gov/pubmed/28936311 http://dx.doi.org/10.1039/c4sc02090a |