Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma

CIC (also known as Capicua) is a transcriptional repressor negatively regulated by RAS/MAPK signaling. Whereas the functions of Cic have been well characterized in Drosophila, little is known about its role in mammals. CIC is inactivated in a variety of human tumors and has been implicated recently...

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Detalles Bibliográficos
Autores principales: Simón-Carrasco, Lucía, Graña, Osvaldo, Salmón, Marina, Jacob, Harrys K.C., Gutierrez, Alejandro, Jiménez, Gerardo, Drosten, Matthias, Barbacid, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588927/
https://www.ncbi.nlm.nih.gov/pubmed/28827401
http://dx.doi.org/10.1101/gad.300244.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588927/
https://www.ncbi.nlm.nih.gov/pubmed/28827401
http://dx.doi.org/10.1101/gad.300244.117

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