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Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC–MS/MS

OBJECTIVES: To present the validation and clinical application of a LC–MS/MS method for the quantification of lamivudine (3TC), emtricitabine (FTC) and tenofovir (TFV) in dried blood spots (DBS) and dried breast milk spots (DBMS). METHODS: DBS and DBMS were prepared from 50 and 30 μL of drug-spiked...

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Detalles Bibliográficos
Autores principales: Waitt, Catriona, Diliiy Penchala, Sujan, Olagunju, Adeniyi, Amara, Alieu, Else, Laura, Lamorde, Mohammed, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588985/
https://www.ncbi.nlm.nih.gov/pubmed/28651173
http://dx.doi.org/10.1016/j.jchromb.2017.06.012