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LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice

Nogo receptor-1 (NgR1) and its ligands inhibit neuronal plasticity and limit functional recovery after brain damage such as ischemic stroke. We have previously shown that lateral olfactory tract usher substance (LOTUS) antagonizes NgR1-mediated signaling. Here, we investigated whether LOTUS enhances...

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Detalles Bibliográficos
Autores principales: Takase, Hajime, Kurihara, Yuji, Yokoyama, Taka-akira, Kawahara, Nobutaka, Takei, Kohtaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589167/
https://www.ncbi.nlm.nih.gov/pubmed/28880879
http://dx.doi.org/10.1371/journal.pone.0184258