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Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient

We present an exceptional case of a patient with high-grade serous ovarian cancer, treated with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions with concomitant progression of other lesions during a treatment-free period. Using immunogenomic approaches, we found t...

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Detalles Bibliográficos
Autores principales: Jiménez-Sánchez, Alejandro, Memon, Danish, Pourpe, Stephane, Veeraraghavan, Harini, Li, Yanyun, Vargas, Hebert Alberto, Gill, Michael B., Park, Kay J., Zivanovic, Oliver, Konner, Jason, Ricca, Jacob, Zamarin, Dmitriy, Walther, Tyler, Aghajanian, Carol, Wolchok, Jedd D., Sala, Evis, Merghoub, Taha, Snyder, Alexandra, Miller, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589211/
https://www.ncbi.nlm.nih.gov/pubmed/28841418
http://dx.doi.org/10.1016/j.cell.2017.07.025