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Large scale expression and purification of secreted mouse hephaestin

Hephaestin is a large membrane-anchored multicopper ferroxidase involved in mammalian iron metabolism. Newly absorbed dietary iron is exported across the enterocyte basolateral membrane by the ferrous iron transporter ferroportin, but hephaestin increases the efficiency of this process by oxidizing...

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Detalles Bibliográficos
Autores principales: Deshpande, Chandrika N., Xin, Vicky, Lu, Yan, Savage, Tom, Anderson, Gregory J., Jormakka, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589216/
https://www.ncbi.nlm.nih.gov/pubmed/28880952
http://dx.doi.org/10.1371/journal.pone.0184366