Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis

The pro-apoptotic BCL2 gene family member, BAX, plays a pivotal role in the intrinsic apoptotic pathway. Under cellular stress, BAX recruitment to the mitochondria occurs when activated BAX forms dimers, then oligomers, to initiate mitochondria outer membrane permeabilization (MOMP), a process criti...

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Detalles Bibliográficos
Autores principales: Maes, Margaret E., Schlamp, Cassandra L., Nickells, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589231/
https://www.ncbi.nlm.nih.gov/pubmed/28880942
http://dx.doi.org/10.1371/journal.pone.0184434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589231/
https://www.ncbi.nlm.nih.gov/pubmed/28880942
http://dx.doi.org/10.1371/journal.pone.0184434

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