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Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis

The pro-apoptotic BCL2 gene family member, BAX, plays a pivotal role in the intrinsic apoptotic pathway. Under cellular stress, BAX recruitment to the mitochondria occurs when activated BAX forms dimers, then oligomers, to initiate mitochondria outer membrane permeabilization (MOMP), a process criti...

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Detalles Bibliográficos
Autores principales:	Maes, Margaret E., Schlamp, Cassandra L., Nickells, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589231/ https://www.ncbi.nlm.nih.gov/pubmed/28880942 http://dx.doi.org/10.1371/journal.pone.0184434

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