Cargando…

ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics

ADP-ribosylation factor 6 (ARF6) is a small GTPase necessary for regulating cellular structure, motility, and vesicle trafficking. In several cellular systems, ARF6 was shown to regulate actin dynamics in coordination with Rac1, a Rho small GTPase. We examined the function of ARF6 in the kidney podo...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jamie S., Jeon, Jin Seok, Fan, Qingfeng, Wong, Hetty N., Palmer, Matthew B., Holzman, Lawrence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589247/
https://www.ncbi.nlm.nih.gov/pubmed/28880939
http://dx.doi.org/10.1371/journal.pone.0184575