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Mapping the STK4/Hippo signaling network in prostate cancer cell

Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. However, how STK4 restricts the emergence of aggressive cancer remains elusive. Here, we investigated the effects of STK4, primarily localized in the cytoplasm,...

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Detalles Bibliográficos
Autores principales: Ready, Damien, Yagiz, Kader, Amin, Pooneh, Yildiz, Yuksel, Funari, Vincent, Bozdag, Serdar, Cinar, Bekir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589252/
https://www.ncbi.nlm.nih.gov/pubmed/28880957
http://dx.doi.org/10.1371/journal.pone.0184590