Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases

During lytic Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, the viral endonu- clease SOX promotes widespread degradation of cytoplasmic messenger RNA (mRNA). However, select mRNAs, including the transcript encoding interleukin-6 (IL-6), escape SOX-induced cleavage. IL-6 escape is mediated...

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Detalles Bibliográficos
Autores principales: Muller, Mandy, Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589255/
https://www.ncbi.nlm.nih.gov/pubmed/28841715
http://dx.doi.org/10.1371/journal.ppat.1006593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589255/
https://www.ncbi.nlm.nih.gov/pubmed/28841715
http://dx.doi.org/10.1371/journal.ppat.1006593

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