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Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases
During lytic Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, the viral endonu- clease SOX promotes widespread degradation of cytoplasmic messenger RNA (mRNA). However, select mRNAs, including the transcript encoding interleukin-6 (IL-6), escape SOX-induced cleavage. IL-6 escape is mediated...
Autores principales: | Muller, Mandy, Glaunsinger, Britt A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589255/ https://www.ncbi.nlm.nih.gov/pubmed/28841715 http://dx.doi.org/10.1371/journal.ppat.1006593 |
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