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ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism

Estrogen-related receptor alpha (ERRα) is an orphan nuclear factor that is a master regulator of cellular energy metabolism. ERRα is overexpressed in a variety of tumors, including ovarian, prostate, colorectal, cervical and breast, and is associated with a more aggressive tumor and a worse outcome....

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Detalles Bibliográficos
Autores principales: Berman, Adi Y, Manna, Subrata, Schwartz, Naomi S, Katz, Yardena E, Sun, Yang, Behrmann, Catherine A, Yu, Jane J, Plas, David R, Alayev, Anya, Holz, Marina K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589335/
https://www.ncbi.nlm.nih.gov/pubmed/28890840
http://dx.doi.org/10.1038/sigtrans.2017.35