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A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus

Traumatic life experiences are associated with alcohol use problems, an association that is likely to be moderated by genetic predisposition. To understand these interactions, we conducted a gene-by-environment genome-wide interaction study (GEWIS) of alcohol use problems in two independent samples,...

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Detalles Bibliográficos
Autores principales: Polimanti, Renato, Kaufman, Joan, Zhao, Hongyu, Kranzler, Henry R., Ursano, Robert J., Kessler, Ronald C., Gelernter, Joel, Stein, Murray B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589475/
https://www.ncbi.nlm.nih.gov/pubmed/28265120
http://dx.doi.org/10.1038/mp.2017.24