Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination

The lethality of the aggressive brain tumor glioblastoma multiforme (GBM) results in part from its strong propensity to invade surrounding normal brain tissue. While oncogenic drivers such as EGFR activation and PTEN loss are thought to promote the motility and invasiveness of GBM cells via PI3K act...

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Detalles Bibliográficos
Autores principales: Wald, Jessica H., Hatakeyama, Jason, Printsev, Ignat, Cuevas, Antonio, Fry, William H.D., Saldana, Matthew J., Vorst, Kacey Vander, Rowson-Hodel, Ashley, Angelastro, James M., Sweeney, Colleen, Carraway, Kermit L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589482/
https://www.ncbi.nlm.nih.gov/pubmed/28481871
http://dx.doi.org/10.1038/onc.2017.126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589482/
https://www.ncbi.nlm.nih.gov/pubmed/28481871
http://dx.doi.org/10.1038/onc.2017.126

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