Cargando…

Thermodynamic properties of amyloid fibrils in equilibrium

In this manuscript we use a two-dimensional coarse-grained model to study how amyloid fibrils grow towards an equilibrium state where they coexist with proteins dissolved in a solution. Free-energies to dissociate proteins from fibrils are estimated from the residual concentration of dissolved prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Urbic, Tomaz, Najem, Sara, Dias, Cristiano L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589490/
https://www.ncbi.nlm.nih.gov/pubmed/28318905
http://dx.doi.org/10.1016/j.bpc.2017.03.001